Basic Information
ID: ALA4826166
Type: Binding
Description: Protac activity at CRBN/EGFR L858R/T790M mutant in human NCI-H1975 cells assessed as increase in ratio of LC3B2 to LC3B1 at 30 to 300 nM preincubated for 2 hrs in presence of Rapamycin and measured after 16 hrs by Western blot assay
Organism: Homo sapiens
Cell type: NCI-H1975
Activity Charts
Bioactivity
Activity Types for Assay ALA4826166
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 868.37 | 5.67 | 5.67 |
| 854.34 | 5.28 | 5.28 |