Assay Report Card

Basic Information

ID: ALA4826168

Type: Binding

Description: Protac activity at CRBN/EGFR L858R/T790M mutant in human NCI-H1975 cells assessed as increase in EGFR protein level at 30 to 500 nM measured after 16 to 48 hrs by Western blot assay relative to control

Organism: Homo sapiens

Cell type: NCI-H1975

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
485.954.394.39