Assay Report Card

Basic Information

ID: ALA4826169

Type: Binding

Description: Protac activity at CRBN/EGFR L858R/T790M mutant in human NCI-H1975 cells assessed as induction of EGFR degradation at 30 to 500 nM by Western blot assay

Organism: Homo sapiens

Cell type: NCI-H1975

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
868.375.675.67
854.345.285.28