Basic Information
ID: ALA4826639
Type: Binding
Description: Inhibition of TNFalpha-induced NFkappaB activation in human A549 cells at 10 uM preincubated for 30 mins followed by TNFalpha stimulation for 6 hrs by luciferase reporter gene assay relative to control
Format: BAO_0000219
Organism: Homo sapiens
Cell type: A549
Target: Nuclear factor NF-kappa-B complex(ALA2094258)
Document: ALA4825685
Inhibition of TNFalpha-induced NFkappaB activation in human A549 cells at 10 uM preincubated for 30 mins followed by TNFalpha stimulation for 6 hrs by luciferase reporter gene assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4826639
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 396.41 | 5.79 | 5.79 |
| 475.30 | 6.56 | 6.56 |
| 507.44 | 7.49 | 7.49 |
| 495.38 | 7.37 | 7.37 |
| 497.36 | 6.16 | 6.16 |
| 475.30 | 6.56 | 6.56 |
| 552.48 | 8.65 | 8.65 |
| 434.47 | 6.75 | 6.75 |
| 495.38 | 7.37 | 7.37 |
| 491.37 | 6.72 | 6.72 |
| 400.47 | 4.89 | 4.89 |
| 494.39 | 6.91 | 6.91 |
| 358.41 | 3.98 | 3.98 |
| 402.41 | 3.45 | 3.45 |
| 392.39 | 3.82 | 3.82 |
| 412.38 | 4.69 | 4.69 |
| 446.36 | 4.71 | 4.71 |
| 384.44 | 4.16 | 4.16 |
| 376.39 | 4.12 | 4.12 |
| 450.93 | 7.26 | 7.26 |
| 474.31 | 6.09 | 6.09 |
| 428.37 | 4.57 | 4.57 |
| 386.42 | 3.61 | 3.61 |
| 484.48 | 7.63 | 7.63 |
| 388.39 | 3.40 | 3.40 |
| 430.37 | 4.83 | 4.83 |
| 446.51 | 6.62 | 6.62 |
| 418.46 | 5.40 | 5.40 |
| 396.81 | 4.47 | 4.47 |
| 374.40 | 3.68 | 3.68 |
| 495.38 | 7.37 | 7.37 |