Basic Information
ID: ALA4827167
Type: Toxicity
Description: Selectivity index, ratio of IC50 for cytotoxicity against rat L6 cells to IC50 for antiplasmodial activity against chloroquine and pyrimethamine resistant Plasmodium falciparum K1 infected in human red blood cells
Format: BAO_0000219
Target: ADMET(ALA612558)
Document: ALA4825701
Selectivity index, ratio of IC50 for cytotoxicity against rat L6 cells to IC50 for antiplasmodial activity against chloroquine and pyrimethamine resistant Plasmodium falciparum K1 infected in human red blood cells: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4827167
Selectivity Index
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 340.43 | 2.88 | 2.88 |
| 304.35 | 3.18 | 3.18 |
| 347.38 | 3.23 | 3.23 |
| 391.43 | 3.07 | 3.07 |
| 342.45 | 3.44 | 3.44 |
| 407.43 | 3.20 | 3.20 |
| 328.42 | 3.51 | 3.51 |
| 328.42 | 3.51 | 3.51 |
| 331.38 | 3.11 | 3.11 |
| 402.50 | 3.40 | 3.40 |
| 332.41 | 3.03 | 3.03 |
| 388.47 | 3.48 | 3.48 |
| 586.74 | 3.96 | 3.96 |
| 342.45 | 3.44 | 3.44 |
| 329.41 | 2.91 | 2.91 |
| 402.50 | 3.40 | 3.40 |