Assay Report Card

Basic Information

ID: ALA4827168

Type: Functional

Description: Antitrypanosomal activity against bloodstream form of Trypanosoma brucei rhodesiense STIB900 infected in mouse assessed as reduction in parasitemia by measuring time taken to cure at 5 mg/kg, ip measured up to 60 days (Rvb = 11 days)

Organism: Trypanosoma brucei rhodesiense

Strain: STIB900

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
340.432.882.88
304.353.183.18
347.383.233.23
342.453.443.44
328.423.513.51
328.423.513.51
331.383.113.11
332.413.033.03
342.453.443.44
329.412.912.91