Basic Information
ID: ALA4827365
Type: ADME
Description: Intrinsic clearance in rat liver microsomes at 1 uM preincubated for 5 mins followed by NADPH addition and measured up to 60 mins by LC-MS/MS analysis
Organism: Rattus norvegicus
Tissue: Liver
Subcellular Fraction: Microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA4827365
CL
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 503.58 | 5.81 | 5.81 |
| 522.56 | 4.87 | 4.87 |
| 504.57 | 5.21 | 5.21 |
| 537.57 | 5.22 | 5.22 |
| 540.55 | 5.00 | 5.00 |
| 519.58 | 4.78 | 4.78 |
| 493.52 | 5.33 | 5.33 |
| 514.57 | 5.31 | 5.31 |
| 468.59 | 4.93 | 4.93 |
| 536.59 | 5.52 | 5.52 |
| 519.58 | 4.78 | 4.78 |
| 504.57 | 5.21 | 5.21 |
| 521.56 | 3.86 | 3.86 |
| 520.57 | 3.89 | 3.89 |
| 523.55 | 4.83 | 4.83 |
| 511.51 | 5.62 | 5.62 |
| 536.55 | 4.25 | 4.25 |
| 517.57 | 4.80 | 4.80 |
| 510.55 | 4.77 | 4.77 |
| 462.44 | 4.51 | 4.51 |
| 501.55 | 4.54 | 4.54 |
| 504.57 | 4.92 | 4.92 |
| 504.57 | 4.73 | 4.73 |
| 540.55 | 5.00 | 5.00 |
| 522.56 | 4.72 | 4.72 |
| 513.60 | 5.10 | 5.10 |
| 511.54 | 4.74 | 4.74 |
| 486.58 | 5.07 | 5.07 |
| 540.55 | 5.16 | 5.16 |
| 523.55 | 4.69 | 4.69 |
| 554.58 | 5.06 | 5.06 |
| 540.55 | 5.00 | 5.00 |
| 536.59 | 5.26 | 5.26 |
| 540.55 | 5.00 | 5.00 |
| 487.57 | 3.98 | 3.98 |
| 486.58 | 4.59 | 4.59 |