Basic Information
ID: ALA4827441
Type: Binding
Description: Displacement of Alexa Fluor 647 labelled ligand from 6His-tagged BRD4 BD1/BD2 Y390A mutant (1 to 477 residue) (unknown origin) measured after 30 mins by TR-FRET assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4827441
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 459.59 | 3.74 | 3.74 |
| 439.56 | 2.48 | 2.48 |
| 487.60 | 3.12 | 3.12 |
| 407.47 | 1.37 | 1.37 |
| 432.52 | 2.50 | 2.50 |
| 432.52 | 2.50 | 2.50 |
| 444.58 | 4.54 | 4.54 |
| 502.62 | 2.90 | 2.90 |
| 374.48 | 3.99 | 3.99 |
| 445.56 | 3.49 | 3.49 |
| 385.46 | 1.66 | 1.66 |
| 432.52 | 2.50 | 2.50 |
| 417.51 | 2.71 | 2.71 |
| 383.49 | 2.32 | 2.32 |
| 445.56 | 3.49 | 3.49 |
| 471.60 | 4.03 | 4.03 |
| 447.54 | 2.21 | 2.21 |
| 407.47 | 1.37 | 1.37 |
| 431.54 | 3.10 | 3.10 |
| 447.54 | 2.80 | 2.80 |
| 445.56 | 3.49 | 3.49 |
| 403.48 | 2.45 | 2.45 |
| 459.59 | 3.30 | 3.30 |
| 473.62 | 4.13 | 4.13 |
| 473.62 | 3.69 | 3.69 |
| 431.54 | 3.10 | 3.10 |
| 425.53 | 2.09 | 2.09 |
| 502.62 | 2.90 | 2.90 |
| 431.54 | 3.10 | 3.10 |
| 473.57 | 2.73 | 2.73 |
| 435.57 | 3.04 | 3.04 |
| 471.60 | 3.88 | 3.88 |
| 457.57 | 3.49 | 3.49 |
| 432.52 | 2.50 | 2.50 |
| 431.54 | 3.48 | 3.48 |
| 443.55 | 3.25 | 3.25 |
| 369.47 | 2.08 | 2.08 |
| 448.56 | 3.63 | 3.63 |
| 399.49 | 3.88 | 3.88 |
| 430.55 | 4.33 | 4.33 |
| 355.44 | 1.69 | 1.69 |
| 457.57 | 3.64 | 3.64 |
| 431.54 | 3.18 | 3.18 |