Basic Information
ID: ALA4827622
Type: Binding
Description: Inhibition of METTL3-mediated m6A methylation in human MOLM-3 cells assessed as reduction in mRNA level measured after 24 hrs by LC-MS/MS analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: MOLM-13
Target: N6-adenosine-methyltransferase catalytic subunit(ALA4739695)
Document: ALA4825715
Inhibition of METTL3-mediated m6A methylation in human MOLM-3 cells assessed as reduction in mRNA level measured after 24 hrs by LC-MS/MS analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4827622
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 504.59 | 3.35 | 3.35 |
| 520.57 | 3.30 | 3.30 |
| 502.54 | 1.70 | 1.70 |
| 531.55 | 3.41 | 3.41 |
| 516.54 | 2.63 | 2.63 |
| 504.52 | 3.85 | 3.85 |