Inhibition of human PARL transfected in HEK293T cell membrane assessed as inhibition of FP-Rh labeling treated with compound for 30 mins prior to FP-R...

Basic Information

ID: ALA4827762

Type: Binding

Description: Inhibition of human PARL transfected in HEK293T cell membrane assessed as inhibition of FP-Rh labeling treated with compound for 30 mins prior to FP-Rh addition by competitive ABPP based analysis

Format: BAO_0000249

Organism: Homo sapiens

Cell type: HEK293T

Subcellular Fraction: Membrane

Target: Presenilins-associated rhomboid-like protein, mitochondrial(ALA4879516)

Document: ALA4825728

Inhibition of human PARL transfected in HEK293T cell membrane assessed as inhibition of FP-Rh labeling treated with compound for 30 mins prior to FP-Rh addition by competitive ABPP based analysis: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4827762

IC50

Total(6)

Parent Molecular Weight	ALogP	Polar Surface Area
284.25	0.43	0.43
331.35	2.12	2.12
351.77	2.30	2.30
315.35	2.19	2.19
239.25	0.52	0.52
255.25	0.46	0.46

Parent Molecular Weight

ALogP

Polar Surface Area

284.25

0.43

331.35

2.12

351.77

2.30

315.35

2.19

239.25

0.52

255.25

0.46

Inhibition of human PARL transfected in HEK293T cell membrane assessed as inhibition of FP-Rh labeling treated with compound for 30 mins prior to FP-R...

Basic Information

Activity Charts

Compound Summary