Ratio of fEC50 for in vivo antagonist activity at TRPA1 in AITC-induced rat pain model assessed as reduction in pain behaviour when administered orall...

Basic Information

ID: ALA4828037

Type: ADME

Description: Ratio of fEC50 for in vivo antagonist activity at TRPA1 in AITC-induced rat pain model assessed as reduction in pain behaviour when administered orally to IC50 for antagonist activity at rat TRPA1

Format: BAO_0000218

Organism: Rattus norvegicus

Target:  ADMET(ALA612558)

Document:  ALA4825747

Ratio of fEC50 for in vivo antagonist activity at TRPA1 in AITC-induced rat pain model assessed as reduction in pain behaviour when administered orally to IC50 for antagonist activity at rat TRPA1: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
559.493.643.64
412.842.462.46
404.791.691.69
609.504.524.52
412.842.102.10
423.862.062.06