Basic Information
ID: ALA4828190
Type: ADME
Description: Inhibition of recombinant human N-terminal His6-tagged full length P110beta/full length untagged human p85alpha expressed in baculovirus infected Sf21 insect cells using PIP2 as substrate preincubated for 15 mins followed by substrate addition and measured after 60 mins by HTRF assay
Organism: Homo sapiens
Cell type: Sf21
Activity Charts
Bioactivity
Activity Types for Assay ALA4828190
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 584.72 | 3.45 | 3.45 |
| 566.73 | 3.32 | 3.32 |
| 602.71 | 3.59 | 3.59 |
| 584.72 | 3.45 | 3.45 |
| 599.73 | 3.91 | 3.91 |
| 598.75 | 3.84 | 3.84 |
| 571.68 | 3.54 | 3.54 |
| 346.41 | 2.69 | 2.69 |
| 549.70 | 4.29 | 4.29 |
| 480.59 | 3.82 | 3.82 |
| 346.41 | 2.69 | 2.69 |
| 563.72 | 4.28 | 4.28 |
| 442.54 | 2.81 | 2.81 |
| 566.73 | 3.32 | 3.32 |
| 514.65 | 1.50 | 1.50 |
| 563.72 | 4.28 | 4.28 |
| 361.42 | 2.40 | 2.40 |
| 520.66 | 4.74 | 4.74 |
| 521.64 | 3.16 | 3.16 |
| 584.72 | 3.45 | 3.45 |
| 506.63 | 4.35 | 4.35 |
| 509.63 | 3.39 | 3.39 |
| 535.67 | 3.50 | 3.50 |
| 550.68 | 4.37 | 4.37 |
| 526.68 | 4.80 | 4.80 |
| 527.62 | 3.52 | 3.52 |
| 527.62 | 3.52 | 3.52 |
| 511.65 | 2.47 | 2.47 |
| 506.63 | 4.35 | 4.35 |
| 564.71 | 3.68 | 3.68 |
| 361.42 | 2.40 | 2.40 |
| 626.78 | 3.71 | 3.71 |
| 444.56 | 2.75 | 2.75 |
| 498.61 | 2.55 | 2.55 |