Basic Information
ID: ALA4828191
Type: Binding
Description: Inhibition of recombinant human N-terminal His6-tagged full length P120gamma expressed in baculovirus infected Sf21 insect cells using PIP2 as substrate preincubated for 15 mins followed by substrate addition and measured after 60 mins by HTRF assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Sf21
Target: PI3-kinase p110-gamma subunit(ALA3267)
Document: ALA4825755
Inhibition of recombinant human N-terminal His6-tagged full length P120gamma expressed in baculovirus infected Sf21 insect cells using PIP2 as substrate preincubated for 15 mins followed by substrate addition and measured after 60 mins by HTRF assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4828191
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 584.72 | 3.45 | 3.45 |
| 566.73 | 3.32 | 3.32 |
| 584.72 | 3.45 | 3.45 |
| 599.73 | 3.91 | 3.91 |
| 598.75 | 3.84 | 3.84 |
| 571.68 | 3.54 | 3.54 |
| 346.41 | 2.69 | 2.69 |
| 549.70 | 4.29 | 4.29 |
| 480.59 | 3.82 | 3.82 |
| 346.41 | 2.69 | 2.69 |
| 563.72 | 4.28 | 4.28 |
| 442.54 | 2.81 | 2.81 |
| 566.73 | 3.32 | 3.32 |
| 514.65 | 1.50 | 1.50 |
| 563.72 | 4.28 | 4.28 |
| 361.42 | 2.40 | 2.40 |
| 648.73 | 3.59 | 3.59 |
| 520.66 | 4.74 | 4.74 |
| 521.64 | 3.16 | 3.16 |
| 584.72 | 3.45 | 3.45 |
| 506.63 | 4.35 | 4.35 |
| 535.67 | 3.50 | 3.50 |
| 550.68 | 4.37 | 4.37 |
| 526.68 | 4.80 | 4.80 |
| 527.62 | 3.52 | 3.52 |
| 527.62 | 3.52 | 3.52 |
| 511.65 | 2.47 | 2.47 |
| 506.63 | 4.35 | 4.35 |
| 564.71 | 3.68 | 3.68 |
| 361.42 | 2.40 | 2.40 |
| 626.78 | 3.71 | 3.71 |
| 444.56 | 2.75 | 2.75 |
| 555.66 | 3.39 | 3.39 |
| 498.61 | 2.55 | 2.55 |