Basic Information
ID: ALA4828192
Type: Binding
Description: Inhibition of PI3Kdelta in human whole blood assessed as reduction in cytostim-stimulated IFNgamma production preincubated for 1 hr followed by cytostim stimulation and measured after 20 hrs by electrochemiluminescence assay
Organism: Homo sapiens
Tissue: Blood
Activity Charts
Bioactivity
Activity Types for Assay ALA4828192
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 580.76 | 3.71 | 3.71 |
| 584.72 | 3.45 | 3.45 |
| 566.73 | 3.32 | 3.32 |
| 602.71 | 3.59 | 3.59 |
| 584.72 | 3.45 | 3.45 |
| 599.73 | 3.91 | 3.91 |
| 598.75 | 3.84 | 3.84 |
| 571.68 | 3.54 | 3.54 |
| 346.41 | 2.69 | 2.69 |
| 549.70 | 4.29 | 4.29 |
| 480.59 | 3.82 | 3.82 |
| 346.41 | 2.69 | 2.69 |
| 563.72 | 4.28 | 4.28 |
| 442.54 | 2.81 | 2.81 |
| 566.73 | 3.32 | 3.32 |
| 514.65 | 1.50 | 1.50 |
| 563.72 | 4.28 | 4.28 |
| 361.42 | 2.40 | 2.40 |
| 520.66 | 4.74 | 4.74 |
| 521.64 | 3.16 | 3.16 |
| 506.63 | 4.35 | 4.35 |
| 509.63 | 3.39 | 3.39 |
| 535.67 | 3.50 | 3.50 |
| 550.68 | 4.37 | 4.37 |
| 526.68 | 4.80 | 4.80 |
| 527.62 | 3.52 | 3.52 |
| 527.62 | 3.52 | 3.52 |
| 511.65 | 2.47 | 2.47 |
| 506.63 | 4.35 | 4.35 |
| 564.71 | 3.68 | 3.68 |
| 361.42 | 2.40 | 2.40 |
| 444.56 | 2.75 | 2.75 |
| 630.74 | 3.45 | 3.45 |
| 498.61 | 2.55 | 2.55 |