Microsomal stability in human liver microsomes assessed as intrinsic clearance at 100 uM preincubated for 10 mins with NADPH followed by compound addi...

Basic Information

ID: ALA4828505

Type: ADME

Description: Microsomal stability in human liver microsomes assessed as intrinsic clearance at 100 uM preincubated for 10 mins with NADPH followed by compound addition and measured upto 30 mins by LC-MS/MS analysis

Format: BAO_0000251

Organism: Homo sapiens

Tissue: Liver

Subcellular Fraction: Microsome

Target:  ADMET(ALA612558)

Document:  ALA4825765

Microsomal stability in human liver microsomes assessed as intrinsic clearance at 100 uM preincubated for 10 mins with NADPH followed by compound addition and measured upto 30 mins by LC-MS/MS analysis: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
550.463.363.36
564.493.753.75
528.513.513.51