Basic Information
ID: ALA4828520
Type: Binding
Description: Inhibition of biotinylated H3K27Me3 peptide (19 to 33 residues) binding to His-tagged EED (1 to 441 residues) (unknown origin) preincubated for 15 mins followed by H3K27Me3 addition and measured after 30 mins by alphascreen competition binding assay
Format: BAO_0000357
Organism: Homo sapiens
Target: Polycomb protein EED(ALA2189117)
Document: ALA4825765
Inhibition of biotinylated H3K27Me3 peptide (19 to 33 residues) binding to His-tagged EED (1 to 441 residues) (unknown origin) preincubated for 15 mins followed by H3K27Me3 addition and measured after 30 mins by alphascreen competition binding assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4828520
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 369.41 | 2.40 | 2.40 |
| 486.66 | 2.92 | 2.92 |
| 423.47 | 2.03 | 2.03 |
| 485.44 | 2.99 | 2.99 |
| 558.54 | 2.87 | 2.87 |
| 570.55 | 3.28 | 3.28 |
| 556.52 | 2.62 | 2.62 |
| 417.44 | 1.97 | 1.97 |
| 597.62 | 3.44 | 3.44 |
| 550.46 | 3.36 | 3.36 |
| 486.43 | 2.39 | 2.39 |
| 598.60 | 4.05 | 4.05 |
| 540.52 | 3.65 | 3.65 |
| 568.45 | 3.66 | 3.66 |
| 586.55 | 2.51 | 2.51 |
| 584.57 | 3.26 | 3.26 |
| 431.47 | 2.01 | 2.01 |
| 486.43 | 2.39 | 2.39 |
| 584.57 | 3.52 | 3.52 |
| 564.49 | 3.75 | 3.75 |
| 432.46 | 1.68 | 1.68 |
| 403.42 | 2.29 | 2.29 |
| 435.43 | 2.11 | 2.11 |
| 421.44 | 0.71 | 0.71 |
| 403.42 | 3.18 | 3.18 |
| 500.46 | 2.73 | 2.73 |
| 435.43 | 2.11 | 2.11 |
| 485.44 | 2.99 | 2.99 |
| 528.51 | 3.51 | 3.51 |
| 526.49 | 3.26 | 3.26 |
| 435.43 | 2.11 | 2.11 |
| 418.43 | 1.37 | 1.37 |
| 514.48 | 3.12 | 3.12 |
| 423.47 | 2.03 | 2.03 |
| 576.50 | 3.90 | 3.90 |