Microsomal stability in rat liver microsomes assessed as intrinsic clearance at 100 uM preincubated for 10 mins with NADPH followed by compound additi...

Basic Information

ID: ALA4828521

Type: ADME

Description: Microsomal stability in rat liver microsomes assessed as intrinsic clearance at 100 uM preincubated for 10 mins with NADPH followed by compound addition and measured upto 30 mins by LC-MS/MS analysis

Format: BAO_0000251

Organism: Rattus norvegicus

Tissue: Liver

Subcellular Fraction: Microsome

Target:  ADMET(ALA612558)

Document:  ALA4825765

Microsomal stability in rat liver microsomes assessed as intrinsic clearance at 100 uM preincubated for 10 mins with NADPH followed by compound addition and measured upto 30 mins by LC-MS/MS analysis: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
550.463.363.36
564.493.753.75
528.513.513.51