Potency index, ratio of ceritinib IC50 to test compound IC50 for human NCI-H2228 cells harboring EML4/ALK L1196M mutant assessed as inhibition of cell...

Basic Information

ID: ALA4829032

Type: Functional

Description: Potency index, ratio of ceritinib IC50 to test compound IC50 for human NCI-H2228 cells harboring EML4/ALK L1196M mutant assessed as inhibition of cell proliferation measured after 72 hrs by CCK8 assay

Format: BAO_0000219

Organism: Homo sapiens

Cell type: NCI-H2228

Target:  NCI-H2228(ALA1075536)

Document:  ALA4828709

Potency index, ratio of ceritinib IC50 to test compound IC50 for human NCI-H2228 cells harboring EML4/ALK L1196M mutant assessed as inhibition of cell proliferation measured after 72 hrs by CCK8 assay: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
589.124.994.99
589.125.585.58