Basic Information
ID: ALA4829033
Type: Functional
Description: Potency index, ratio of crizotinib IC50 to test compound IC50 for human NCI-H2228 cells harboring EML4/ALK L1196M mutant assessed as inhibition of cell proliferation measured after 72 hrs by CCK8 assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: NCI-H2228
Target: NCI-H2228(ALA1075536)
Document: ALA4828709
Potency index, ratio of crizotinib IC50 to test compound IC50 for human NCI-H2228 cells harboring EML4/ALK L1196M mutant assessed as inhibition of cell proliferation measured after 72 hrs by CCK8 assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4829033
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 589.12 | 4.99 | 4.99 |
| 589.12 | 5.58 | 5.58 |