Assay Report Card

Basic Information

ID: ALA4829084

Type: Binding

Description: Inhibition of gp120 in HIV-1 subtype B #11578 harboring pseudotyped Env pWEAUd15.410.5017 infected in human TZM-bl cells assessed as reduction in viral infection pretreated for 30 mins before viral infection and measured after 3 days by luciferase based single cycle infection assay

Organism: Human immunodeficiency virus 1

Strain: #11578

Cell type: TZM-bl

Activity Charts

Bioactivity

Activity Types for Assay ALA4829084

IC50

Total(32)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
403.55	2.95	2.95
364.86	2.51	2.51
348.47	2.44	2.44
389.52	3.02	3.02
368.85	1.74	1.74
346.84	3.22	3.22
368.85	1.35	1.35
318.18	2.16	2.16
386.84	0.86	0.86
389.52	3.02	3.02
321.78	2.96	2.96
330.41	1.85	1.85
348.47	2.44	2.44
478.54	4.51	4.51
382.87	1.74	1.74
382.87	1.74	1.74
450.49	3.66	3.66
427.78	1.19	1.19
330.41	1.85	1.85
346.84	3.22	3.22
368.85	1.35	1.35
350.83	2.20	2.20
403.55	2.95	2.95
478.54	4.51	4.51
377.89	4.51	4.51
368.85	1.74	1.74
388.54	3.06	3.06
350.83	2.20	2.20
364.86	2.51	2.51
388.54	3.06	3.06
386.84	0.86	0.86
427.78	1.19	1.19