Assay Report Card

Basic Information

ID: ALA4829089

Type: Binding

Description: Inhibition of gp120 in HIV-1 ADA infected in CD4-negative dog Cf2Th-CCR5 cells assessed as antagonism of viral entry by measuring inhibition of viral infection at 20 to 60 uM pretreated for 30 mins before viral infection and incubated for 48 hrs by luciferase assay

Organism: Human immunodeficiency virus 1

Strain: ADA

Cell type: Cf2Th-CCR5

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
425.442.782.78
346.843.223.22
350.832.202.20