Basic Information
ID: ALA4829124
Type: ADME
Description: Metabolic stability in human liver microsomes assessed as parent compound remaining at 0.5 uM incubated for 10 mins in presence of NADPH by LC-MS/MS analysis
Format: BAO_0000251
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsome
Target: ADMET(ALA612558)
Document: ALA4828715
Metabolic stability in human liver microsomes assessed as parent compound remaining at 0.5 uM incubated for 10 mins in presence of NADPH by LC-MS/MS analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4829124
Stability
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 308.34 | 3.53 | 3.53 |
| 291.33 | 2.79 | 2.79 |
| 323.44 | 3.71 | 3.71 |
| 301.39 | 3.22 | 3.22 |
| 343.43 | 3.59 | 3.59 |
| 323.35 | 2.99 | 2.99 |
| 315.37 | 2.81 | 2.81 |
| 303.37 | 1.59 | 1.59 |
| 303.36 | 2.81 | 2.81 |
| 300.36 | 3.87 | 3.87 |
| 303.37 | 1.79 | 1.79 |
| 298.35 | 2.53 | 2.53 |
| 314.39 | 2.46 | 2.46 |
| 289.34 | 2.42 | 2.42 |
| 347.85 | 3.72 | 3.72 |
| 317.39 | 3.05 | 3.05 |
| 261.28 | 1.64 | 1.64 |
| 303.36 | 2.66 | 2.66 |
| 291.31 | 1.00 | 1.00 |
| 303.36 | 2.81 | 2.81 |
| 301.35 | 2.43 | 2.43 |
| 317.39 | 2.92 | 2.92 |
| 273.34 | 2.65 | 2.65 |
| 287.36 | 2.96 | 2.96 |
| 289.34 | 2.42 | 2.42 |
| 314.39 | 2.46 | 2.46 |
| 342.44 | 3.11 | 3.11 |
| 302.38 | 2.40 | 2.40 |
| 317.39 | 3.05 | 3.05 |
| 343.43 | 3.31 | 3.31 |
| 313.40 | 3.07 | 3.07 |
| 303.36 | 2.66 | 2.66 |
| 343.43 | 3.31 | 3.31 |
| 303.36 | 2.66 | 2.66 |
| 357.33 | 3.55 | 3.55 |
| 317.39 | 2.91 | 2.91 |
| 339.34 | 3.25 | 3.25 |
| 275.31 | 2.03 | 2.03 |
| 289.34 | 2.27 | 2.27 |
| 301.35 | 2.42 | 2.42 |
| 329.40 | 3.20 | 3.20 |
| 288.35 | 3.72 | 3.72 |
| 302.38 | 2.19 | 2.19 |
| 319.43 | 3.13 | 3.13 |
| 315.37 | 2.81 | 2.81 |
| 328.42 | 2.65 | 2.65 |
| 303.36 | 2.66 | 2.66 |
| 283.38 | 3.06 | 3.06 |
| 317.39 | 3.05 | 3.05 |
| 337.38 | 2.86 | 2.86 |