Basic Information
ID: ALA4829384
Type: Binding
Description: Inhibition of human 20S proteasome LMP2 activity in human RPMI-8226 cells overexpressing ABCB1 using Ac-PAL-AMC as fluorogenic substrate incubated for 72 hrs by fluorescence assay
Organism: Homo sapiens
Cell type: RPMI-8226
Activity Charts
Bioactivity
Activity Types for Assay ALA4829384
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 514.62 | 0.73 | 0.73 |
| 415.45 | -0.66 | -0.66 |
| 508.62 | 0.06 | 0.06 |
| 451.56 | 0.94 | 0.94 |
| 522.64 | 0.45 | 0.45 |
| 589.73 | 3.52 | 3.52 |
| 555.72 | 3.33 | 3.33 |