Basic Information
ID: ALA4829580
Type: Binding
Description: Inhibition of [3H]DA uptake at VMAT2 in rat striatal synaptosome incubated for 10 mins followed by [3H]DA addition and measured after 20 mins by TopCount scintillation counting method
Organism: Rattus norvegicus
Tissue: Striatum
Subcellular Fraction: Synaptosome
Activity Charts
Bioactivity
Activity Types for Assay ALA4829580
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 347.50 | 3.81 | 3.81 |
| 317.43 | 3.24 | 3.24 |
| 318.46 | 3.00 | 3.00 |
| 319.45 | 3.03 | 3.03 |
| 387.44 | 3.96 | 3.96 |
| 359.51 | 3.81 | 3.81 |
| 344.46 | 2.92 | 2.92 |
| 333.47 | 3.42 | 3.42 |
| 377.53 | 3.44 | 3.44 |
| 349.47 | 2.39 | 2.39 |
| 333.47 | 3.42 | 3.42 |
| 347.50 | 3.81 | 3.81 |