Basic Information
ID: ALA4829861
Type: Binding
Description: Inhibition of human Cathepsin C in human U-937 cells using H-Gly-Phe-AFC as substrate pretreated for 60 mins followed by substrate addition incubated for 60 mins
Organism: Homo sapiens
Cell type: U-937
Activity Charts
Bioactivity
Activity Types for Assay ALA4829861
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 420.47 | 1.73 | 1.73 |
| 370.81 | 5.64 | 5.64 |
| 328.73 | 4.47 | 4.47 |
| 459.48 | 4.14 | 4.14 |
| 365.75 | 5.03 | 5.03 |
| 447.87 | 6.76 | 6.76 |
| 407.83 | 5.33 | 5.33 |
| 380.76 | 5.52 | 5.52 |
| 450.85 | 4.87 | 4.87 |
| 443.45 | 6.11 | 6.11 |
| 489.93 | 5.32 | 5.32 |
| 364.76 | 5.64 | 5.64 |
| 393.80 | 4.94 | 4.94 |
| 382.75 | 5.78 | 5.78 |
| 407.78 | 4.73 | 4.73 |
| 394.78 | 5.64 | 5.64 |
| 442.85 | 5.04 | 5.04 |
| 389.77 | 5.51 | 5.51 |
| 393.80 | 4.94 | 4.94 |
| 393.80 | 4.94 | 4.94 |
| 466.92 | 5.58 | 5.58 |
| 326.79 | 4.63 | 4.63 |
| 448.88 | 6.02 | 6.02 |
| 464.88 | 4.18 | 4.18 |
| 378.79 | 5.94 | 5.94 |
| 407.83 | 5.33 | 5.33 |
| 477.92 | 5.17 | 5.17 |
| 473.89 | 5.77 | 5.77 |
| 324.82 | 5.18 | 5.18 |
| 314.75 | 4.76 | 4.76 |
| 441.84 | 6.70 | 6.70 |
| 491.95 | 5.56 | 5.56 |
| 503.96 | 5.71 | 5.71 |
| 431.81 | 6.29 | 6.29 |
| 392.81 | 5.55 | 5.55 |
| 338.84 | 5.74 | 5.74 |
| 463.89 | 5.44 | 5.44 |
| 380.76 | 5.52 | 5.52 |
| 463.90 | 4.78 | 4.78 |
| 491.91 | 4.70 | 4.70 |
| 413.43 | 6.11 | 6.11 |
| 460.85 | 6.30 | 6.30 |
| 447.44 | 4.27 | 4.27 |
| 464.88 | 4.18 | 4.18 |
| 462.91 | 5.39 | 5.39 |
| 364.76 | 5.64 | 5.64 |
| 296.76 | 4.62 | 4.62 |
| 314.75 | 4.76 | 4.76 |
| 392.81 | 6.20 | 6.20 |
| 365.75 | 5.03 | 5.03 |
| 443.48 | 4.44 | 4.44 |
| 484.91 | 6.76 | 6.76 |
| 353.81 | 4.58 | 4.58 |
| 382.75 | 5.78 | 5.78 |
| 427.46 | 6.41 | 6.41 |
| 505.93 | 5.09 | 5.09 |
| 491.95 | 5.56 | 5.56 |
| 464.88 | 4.83 | 4.83 |
| 356.78 | 5.25 | 5.25 |
| 406.84 | 5.94 | 5.94 |
| 449.87 | 4.44 | 4.44 |
| 421.81 | 5.59 | 5.59 |
| 445.84 | 5.43 | 5.43 |
| 431.42 | 6.25 | 6.25 |
| 463.90 | 4.96 | 4.96 |
| 463.90 | 4.78 | 4.78 |
| 366.73 | 4.43 | 4.43 |
| 366.73 | 4.43 | 4.43 |
| 406.84 | 6.76 | 6.76 |
| 365.75 | 5.03 | 5.03 |
| 420.87 | 6.93 | 6.93 |
| 310.79 | 4.93 | 4.93 |
| 448.75 | 6.53 | 6.53 |
| 456.86 | 6.28 | 6.28 |