Basic Information
ID: ALA4830655
Type: Toxicity
Description: Selectivity index, ratio of CC50 for human HepDES19 cells to EC50 for inhibition of capsid protein-mediated antiviral activity against HBV infected in human HepDES19 cells assessed as inhibition of DNA replication
Format: BAO_0000219
Target: ADMET(ALA612558)
Document: ALA4828746
Selectivity index, ratio of CC50 for human HepDES19 cells to EC50 for inhibition of capsid protein-mediated antiviral activity against HBV infected in human HepDES19 cells assessed as inhibition of DNA replication: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4830655
Ratio CC50/EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 229.26 | -0.59 | -0.59 |
| 509.40 | 3.29 | 3.29 |
| 565.46 | 3.79 | 3.79 |
| 662.58 | 4.81 | 4.81 |
| 576.49 | 3.56 | 3.56 |
| 662.58 | 4.81 | 4.81 |
| 648.60 | 5.29 | 5.29 |
| 634.57 | 4.90 | 4.90 |
| 562.46 | 3.17 | 3.17 |
| 590.47 | 3.08 | 3.08 |
| 648.60 | 5.29 | 5.29 |
| 648.55 | 4.42 | 4.42 |
| 666.57 | 4.60 | 4.60 |
| 576.49 | 3.56 | 3.56 |
| 562.46 | 3.17 | 3.17 |