Basic Information
ID: ALA4830745
Type: Functional
Description: Agonist activity at human GPR27 expressed in HEK293 cells co-expressing FnLArrb2.GPR27V2LFc assessed as maximal induction of beta-arrestin recruitment incubated for 10 mins measured followed by addition of D-luciferin by firefly-luciferase complementation assay relative to control
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Probable G-protein coupled receptor 27(ALA4523923)
Document: ALA4828750
Agonist activity at human GPR27 expressed in HEK293 cells co-expressing FnLArrb2.GPR27V2LFc assessed as maximal induction of beta-arrestin recruitment incubated for 10 mins measured followed by addition of D-luciferin by firefly-luciferase complementation assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4830745
Emax
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 422.29 | 4.44 | 4.44 |
| 451.33 | 5.06 | 5.06 |
| 435.33 | 4.98 | 4.98 |
| 455.75 | 5.70 | 5.70 |
| 449.30 | 4.64 | 4.64 |
| 423.28 | 3.84 | 3.84 |
| 435.33 | 5.07 | 5.07 |
| 421.31 | 5.05 | 5.05 |
| 461.34 | 4.51 | 4.51 |
| 385.25 | 5.50 | 5.50 |
| 435.33 | 4.72 | 4.72 |
| 445.34 | 4.81 | 4.81 |
| 449.32 | 4.36 | 4.36 |
| 457.36 | 4.60 | 4.60 |
| 496.30 | 4.48 | 4.48 |
| 455.75 | 5.70 | 5.70 |
| 395.42 | 3.75 | 3.75 |
| 465.76 | 5.16 | 5.16 |
| 435.33 | 5.35 | 5.35 |
| 405.84 | 3.93 | 3.93 |
| 404.85 | 4.53 | 4.53 |
| 421.31 | 5.05 | 5.05 |
| 422.84 | 4.67 | 4.67 |
| 455.75 | 5.70 | 5.70 |
| 420.45 | 3.85 | 3.85 |
| 421.31 | 5.05 | 5.05 |
| 422.29 | 4.44 | 4.44 |
| 400.89 | 4.70 | 4.70 |
| 435.33 | 5.35 | 5.35 |
| 402.48 | 4.89 | 4.89 |
| 438.40 | 4.90 | 4.90 |