Basic Information
ID: ALA4831060
Type: Binding
Description: Agonist activity at human TLR8 expressed in HEK-Blue hTLR8 cells assessed as NF-kappaB activation at 10 to 25 uM measured after 24 hrs by SEAP-based colorimetric assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK-Blue hTLR8
Target: Toll-like receptor 8(ALA5805)
Document: ALA4828757
Agonist activity at human TLR8 expressed in HEK-Blue hTLR8 cells assessed as NF-kappaB activation at 10 to 25 uM measured after 24 hrs by SEAP-based colorimetric assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4831060
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 335.35 | 4.84 | 4.84 |
| 325.32 | 4.43 | 4.43 |
| 292.24 | 2.16 | 2.16 |
| 333.31 | 4.41 | 4.41 |
| 302.28 | 2.57 | 2.57 |
| 365.38 | 4.84 | 4.84 |
| 319.29 | 4.37 | 4.37 |
| 269.23 | 3.35 | 3.35 |
| 349.31 | 3.86 | 3.86 |
| 273.21 | 2.16 | 2.16 |
| 269.23 | 3.33 | 3.33 |
| 259.26 | 3.17 | 3.17 |
| 349.31 | 3.86 | 3.86 |
| 273.28 | 3.48 | 3.48 |
| 348.33 | 3.83 | 3.83 |
| 257.32 | 3.41 | 3.41 |
| 283.25 | 3.72 | 3.72 |
| 285.27 | 3.82 | 3.82 |
| 363.30 | 4.07 | 4.07 |
| 305.26 | 4.50 | 4.50 |
| 342.32 | 2.50 | 2.50 |
| 297.28 | 4.11 | 4.11 |
| 311.31 | 4.50 | 4.50 |
| 348.33 | 3.83 | 3.83 |
| 341.40 | 5.22 | 5.22 |
| 271.35 | 3.72 | 3.72 |
| 271.24 | 3.58 | 3.58 |
| 317.27 | 2.18 | 2.18 |
| 345.32 | 4.48 | 4.48 |
| 349.31 | 4.38 | 4.38 |
| 308.33 | 2.95 | 2.95 |
| 257.21 | 3.19 | 3.19 |
| 349.31 | 4.38 | 4.38 |
| 271.24 | 3.58 | 3.58 |
| 335.29 | 4.07 | 4.07 |
| 214.15 | 2.76 | 2.76 |
| 285.27 | 3.97 | 3.97 |
| 283.25 | 3.58 | 3.58 |
| 351.37 | 4.86 | 4.86 |
| 349.38 | 5.14 | 5.14 |
| 335.29 | 4.07 | 4.07 |
| 313.32 | 4.75 | 4.75 |