Basic Information
ID: ALA4831078
Type: Binding
Description: Inhibition of DNA Topoisomerase-2 in human MDA-MB-238 cells assessed as generation of DNA double strand breaks by measuring gamma-H2AX at 2 uM incubated for 24 hrs followed by drug washout and measured after 24 hrs by immunofluorescence assay
Organism: Homo sapiens
Cell type: MDA-MB-238
Activity Charts
Bioactivity
Activity Types for Assay ALA4831078
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 283.33 | 1.58 | 1.58 |
| 532.56 | 4.44 | 4.44 |