Basic Information
ID: ALA4831102
Type: Functional
Description: Antagonist activity at human 5HT6 receptor expressed in human 1321N1 cells assessed as inhibition of serotonin-induced cAMP accumulation incubated for 30 mins by TR-FRET assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: 1321N1
Target: Serotonin 6 (5-HT6) receptor(ALA3371)
Document: ALA4828761
Antagonist activity at human 5HT6 receptor expressed in human 1321N1 cells assessed as inhibition of serotonin-induced cAMP accumulation incubated for 30 mins by TR-FRET assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4831102
Kb
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 487.36 | 2.85 | 2.85 |
| 406.51 | 4.05 | 4.05 |
| 515.68 | 4.05 | 4.05 |
| 475.40 | 5.35 | 5.35 |
| 464.54 | 3.97 | 3.97 |
| 420.53 | 4.36 | 4.36 |
| 513.66 | 4.49 | 4.49 |
| 398.53 | 4.04 | 4.04 |
| 412.56 | 4.43 | 4.43 |
| 408.52 | 3.61 | 3.61 |
| 563.72 | 5.65 | 5.65 |
| 440.95 | 4.70 | 4.70 |
| 464.54 | 3.97 | 3.97 |
| 456.57 | 5.20 | 5.20 |