Basic Information
ID: ALA4831137
Type: Binding
Description: Inhibition of BuChE in human plasma using BTC as substrate at 10 uM preincubated with enzyme for 5 mins followed by substrate addition for 5 mins by Ellman's method relative to control
Format: BAO_0000366
Organism: Homo sapiens
Tissue: Plasma
Target: Butyrylcholinesterase(ALA1914)
Document: ALA4828761
Inhibition of BuChE in human plasma using BTC as substrate at 10 uM preincubated with enzyme for 5 mins followed by substrate addition for 5 mins by Ellman's method relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4831137
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 198.27 | 2.70 | 2.70 |
| 379.50 | 4.36 | 4.36 |
| 487.36 | 2.85 | 2.85 |
| 356.56 | 4.40 | 4.40 |
| 330.41 | 2.48 | 2.48 |
| 406.51 | 4.05 | 4.05 |
| 515.68 | 4.05 | 4.05 |
| 475.40 | 5.35 | 5.35 |
| 464.54 | 3.97 | 3.97 |
| 373.46 | 3.55 | 3.55 |
| 420.53 | 4.36 | 4.36 |
| 464.54 | 3.83 | 3.83 |
| 474.50 | 5.07 | 5.07 |
| 440.95 | 4.70 | 4.70 |
| 451.50 | 3.96 | 3.96 |
| 407.50 | 3.44 | 3.44 |
| 449.58 | 4.11 | 4.11 |
| 431.56 | 4.20 | 4.20 |
| 513.66 | 4.49 | 4.49 |
| 398.53 | 4.04 | 4.04 |
| 412.56 | 4.43 | 4.43 |
| 513.66 | 4.49 | 4.49 |
| 358.49 | 4.42 | 4.42 |
| 463.56 | 4.01 | 4.01 |
| 372.51 | 4.73 | 4.73 |
| 370.50 | 5.17 | 5.17 |
| 480.61 | 3.99 | 3.99 |
| 463.62 | 5.31 | 5.31 |
| 408.52 | 3.61 | 3.61 |
| 563.72 | 5.65 | 5.65 |
| 440.95 | 4.70 | 4.70 |
| 410.50 | 3.95 | 3.95 |
| 356.47 | 4.86 | 4.86 |
| 450.56 | 4.45 | 4.45 |
| 407.50 | 3.44 | 3.44 |
| 440.95 | 4.70 | 4.70 |
| 424.50 | 4.19 | 4.19 |
| 466.56 | 3.53 | 3.53 |
| 436.53 | 4.06 | 4.06 |
| 413.54 | 2.85 | 2.85 |
| 466.56 | 4.06 | 4.06 |
| 465.64 | 4.86 | 4.86 |
| 387.48 | 3.85 | 3.85 |
| 464.54 | 3.97 | 3.97 |
| 479.62 | 4.39 | 4.39 |
| 436.53 | 4.06 | 4.06 |
| 464.54 | 3.82 | 3.82 |
| 449.58 | 4.11 | 4.11 |
| 422.55 | 3.92 | 3.92 |
| 456.57 | 5.20 | 5.20 |
| 420.53 | 4.39 | 4.39 |
| 386.50 | 4.25 | 4.25 |
| 370.47 | 3.26 | 3.26 |
| 514.60 | 5.13 | 5.13 |
| 470.59 | 5.51 | 5.51 |
| 372.47 | 3.94 | 3.94 |
| 450.56 | 4.45 | 4.45 |