Basic Information
ID: ALA4831392
Type: Binding
Description: Inhibition of CHK1 (unknown origin) incubated for 1 hr in presence of ATP by HTRF assay
Format: BAO_0000357
Organism: Homo sapiens
Target: Serine/threonine-protein kinase Chk1(ALA4630)
Document: ALA4828771
Inhibition of CHK1 (unknown origin) incubated for 1 hr in presence of ATP by HTRF assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4831392
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 406.42 | 3.10 | 3.10 |
| 419.46 | 4.23 | 4.23 |
| 393.37 | 2.68 | 2.68 |
| 391.40 | 3.45 | 3.45 |
| 407.40 | 3.02 | 3.02 |
| 363.35 | 2.53 | 2.53 |
| 366.35 | 2.31 | 2.31 |
| 389.39 | 3.20 | 3.20 |
| 392.39 | 2.57 | 2.57 |
| 349.32 | 2.28 | 2.28 |
| 392.39 | 2.71 | 2.71 |
| 389.39 | 3.01 | 3.01 |
| 363.35 | 2.67 | 2.67 |
| 411.39 | 1.25 | 1.25 |
| 379.39 | 3.31 | 3.31 |
| 405.43 | 3.84 | 3.84 |
| 363.35 | 2.67 | 2.67 |
| 450.47 | 2.23 | 2.23 |
| 352.32 | 1.92 | 1.92 |
| 377.37 | 3.06 | 3.06 |
| 418.43 | 3.05 | 3.05 |
| 363.35 | 2.67 | 2.67 |
| 459.44 | 3.00 | 3.00 |
| 380.33 | 1.30 | 1.30 |
| 377.37 | 2.92 | 2.92 |
| 377.37 | 2.92 | 2.92 |
| 392.39 | 2.71 | 2.71 |
| 379.35 | 2.29 | 2.29 |
| 406.42 | 2.96 | 2.96 |
| 363.35 | 2.67 | 2.67 |
| 391.40 | 3.26 | 3.26 |
| 393.37 | 2.68 | 2.68 |
| 406.42 | 3.23 | 3.23 |
| 392.39 | 2.71 | 2.71 |
| 377.37 | 2.92 | 2.92 |
| 351.34 | 2.66 | 2.66 |
| 365.36 | 3.04 | 3.04 |
| 377.37 | 3.19 | 3.19 |
| 395.39 | 2.54 | 2.54 |
| 378.36 | 2.32 | 2.32 |
| 378.36 | 2.32 | 2.32 |
| 377.37 | 3.19 | 3.19 |
| 367.34 | 2.27 | 2.27 |
| 365.36 | 2.87 | 2.87 |
| 407.40 | 2.93 | 2.93 |
| 392.39 | 2.66 | 2.66 |
| 351.34 | 2.53 | 2.53 |
| 406.42 | 3.23 | 3.23 |
| 407.40 | 2.93 | 2.93 |
| 377.37 | 2.92 | 2.92 |
| 351.34 | 2.65 | 2.65 |
| 337.31 | 2.27 | 2.27 |
| 393.37 | 2.68 | 2.68 |
| 365.32 | 2.05 | 2.05 |
| 365.36 | 2.92 | 2.92 |
| 364.33 | 2.64 | 2.64 |
| 381.36 | 1.89 | 1.89 |
| 443.46 | 1.94 | 1.94 |
| 366.35 | 2.18 | 2.18 |
| 365.36 | 2.90 | 2.90 |
| 380.38 | 2.52 | 2.52 |
| 377.37 | 3.06 | 3.06 |
| 379.35 | 1.91 | 1.91 |
| 379.35 | 2.29 | 2.29 |
| 323.28 | 1.88 | 1.88 |
| 408.39 | 1.77 | 1.77 |