ID: ALA4831565
Type: Binding
Description: Inhibition of recombinant human GLS1 expressed in Escherichia coli strain BL21 (DE3) preincubated for 10 mins before glutamine addition and measured after 60 mins by bovine liver glutamate dehydrogenase based coupled enzyme assay
Format: BAO_0000019
Organism: Homo sapiens
Target: Glutaminase kidney isoform, mitochondrial(ALA2146302)
Document: ALA4831477
Inhibition of recombinant human GLS1 expressed in Escherichia coli strain BL21 (DE3) preincubated for 10 mins before glutamine addition and measured after 60 mins by bovine liver glutamate dehydrogenase based coupled enzyme assay: 1
Bioactivity
Activity Types for Assay ALA4831565
IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
524.70 | 4.27 | 4.27 |
571.59 | 4.55 | 4.55 |
604.76 | 5.43 | 5.43 |
598.73 | 5.36 | 5.36 |
632.81 | 6.21 | 6.21 |
654.84 | 6.92 | 6.92 |
570.68 | 4.58 | 4.58 |
626.78 | 6.14 | 6.14 |
626.78 | 6.17 | 6.17 |
562.74 | 6.08 | 6.08 |
576.70 | 4.64 | 4.64 |
660.87 | 6.99 | 6.99 |
576.70 | 4.64 | 4.64 |
511.67 | 4.76 | 4.76 |
632.81 | 6.21 | 6.21 |
604.76 | 5.43 | 5.43 |
660.87 | 6.99 | 6.99 |
652.78 | 5.26 | 5.26 |
548.71 | 5.69 | 5.69 |
520.66 | 4.91 | 4.91 |