Assay Report Card

Basic Information

ID: ALA4831899

Type: Binding

Description: Inhibition of human NF-kB in human HCT-116 cells assessed as suppression of TNF-alpha induced TAK1 phosphorylation at 0.5 to 5 uM pretreated with compounds for 24 hrs followed by TNF-alpha stimulation for 10 mins by Western blot analysis

Organism: Homo sapiens

Cell type: HCT-116

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
404.473.763.76