Basic Information
ID: ALA4832111
Type: Binding
Description: PROTAC activity at CRBN/Bcr-Abl in human K562 cells assessed as reduction in C-Abl level at 30 nM preincubated with NEDD8 inhibitor MLN4924 for 2 hrs and measured after 8 hrs by Western blotting analysis
Organism: Homo sapiens
Cell type: K562
Activity Charts
Bioactivity
Activity Types for Assay ALA4832111
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 760.30 | 4.51 | 4.51 |