Basic Information
ID: ALA4832320
Type: Binding
Description: Inhibition of human KDM4D expressed in Escherichia coli BL21 (DE3) using biotinylated H3-derived peptide and 2-OG as substrate preincubated for 15 mins followed by substrate addition and measured after 1 hr by AlphaLISA assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4832320
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 417.47 | 3.11 | 3.11 |
| 435.46 | 3.25 | 3.25 |
| 430.48 | 3.95 | 3.95 |
| 381.43 | 2.21 | 2.21 |
| 437.50 | 3.68 | 3.68 |
| 478.55 | 4.00 | 4.00 |
| 447.49 | 3.12 | 3.12 |
| 489.57 | 4.87 | 4.87 |
| 489.57 | 4.87 | 4.87 |
| 416.48 | 2.54 | 2.54 |
| 427.50 | 3.55 | 3.55 |
| 455.49 | 3.82 | 3.82 |
| 413.47 | 3.20 | 3.20 |
| 492.58 | 4.30 | 4.30 |
| 477.56 | 4.60 | 4.60 |
| 461.52 | 3.51 | 3.51 |
| 464.92 | 4.60 | 4.60 |
| 428.56 | 2.94 | 2.94 |
| 414.46 | 2.60 | 2.60 |
| 489.57 | 4.87 | 4.87 |
| 470.52 | 3.60 | 3.60 |
| 441.53 | 3.98 | 3.98 |
| 435.46 | 3.25 | 3.25 |
| 395.46 | 2.45 | 2.45 |
| 313.36 | 1.64 | 1.64 |
| 429.52 | 3.49 | 3.49 |
| 464.92 | 4.60 | 4.60 |
| 489.57 | 4.87 | 4.87 |
| 429.52 | 3.49 | 3.49 |
| 437.50 | 3.68 | 3.68 |
| 381.43 | 2.21 | 2.21 |
| 463.53 | 4.36 | 4.36 |
| 479.54 | 3.39 | 3.39 |
| 341.41 | 2.24 | 2.24 |
| 383.45 | 2.45 | 2.45 |
| 397.48 | 2.84 | 2.84 |
| 490.56 | 4.27 | 4.27 |
| 448.47 | 4.09 | 4.09 |
| 423.51 | 3.38 | 3.38 |
| 451.91 | 3.76 | 3.76 |
| 489.57 | 4.87 | 4.87 |
| 490.56 | 4.27 | 4.27 |
| 455.49 | 3.82 | 3.82 |
| 489.57 | 4.87 | 4.87 |
| 438.48 | 3.08 | 3.08 |
| 417.49 | 1.76 | 1.76 |
| 381.43 | 2.21 | 2.21 |
| 461.52 | 3.51 | 3.51 |
| 382.42 | 2.63 | 2.63 |
| 470.52 | 3.60 | 3.60 |
| 447.49 | 3.12 | 3.12 |
| 355.39 | 1.82 | 1.82 |
| 467.52 | 3.69 | 3.69 |
| 412.49 | 2.78 | 2.78 |