Basic Information
ID: ALA4832496
Type: Functional
Description: Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as inhibition of forskolin induced cAMP production by measuring U50,488 Emax at 3 uM pretreated for 30 mins followed by coincubation with U50,488 measured after 30 mins by HTRF assay relative to control
Format: BAO_0000249
Organism: Mus musculus
Cell type: HEK293
Subcellular Fraction: Cell membrane
Target: Kappa opioid receptor(ALA4329)
Document: ALA4831505
Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as inhibition of forskolin induced cAMP production by measuring U50,488 Emax at 3 uM pretreated for 30 mins followed by coincubation with U50,488 measured after 30 mins by HTRF assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4832496
Emax
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 2937.41 |