Basic Information
ID: ALA4832497
Type: Functional
Description: Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as inhibition of forskolin induced cAMP production by measuring U50,488 Emax at 10 uM pretreated for 30 mins followed by coincubation with U50,488 measured after 30 mins by HTRF assay relative to control
Format: BAO_0000249
Organism: Mus musculus
Cell type: HEK293
Subcellular Fraction: Cell membrane
Target: Kappa opioid receptor(ALA4329)
Document: ALA4831505
Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as inhibition of forskolin induced cAMP production by measuring U50,488 Emax at 10 uM pretreated for 30 mins followed by coincubation with U50,488 measured after 30 mins by HTRF assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4832497
Emax
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 2937.41 |