Basic Information
ID: ALA4832500
Type: Binding
Description: Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as beta-arrestin recruitment by measuring U50,488 EC50 at 0.03 uM using furimazine as a substrate pretreated for 5 mins followed by ligand addition coincubation with U50,488 measured for 35 mins by BRET assay
Format: BAO_0000249
Organism: Mus musculus
Cell type: HEK293
Subcellular Fraction: Cell membrane
Target: Kappa opioid receptor(ALA4329)
Document: ALA4831505
Positive allosteric modulator activity in mouse kappa opioid receptor stably expressed in HEK293 cell membrane assessed as beta-arrestin recruitment by measuring U50,488 EC50 at 0.03 uM using furimazine as a substrate pretreated for 5 mins followed by ligand addition coincubation with U50,488 measured for 35 mins by BRET assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4832500
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 2937.41 |