Assay Report Card

Basic Information

ID: ALA4832578

Type: ADME

Description: Metabolic stability in mouse liver microsomes assessed as intrinsic clearance at 0.1 uM preincubated for 10 mins followed by NADPH addition and measured for 60 mins per gm protein by LC-MS/MS analysis

Organism: Mus musculus

Tissue: Liver

Subcellular Fraction: Microsome

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
471.555.835.83
473.885.945.94
483.495.605.60
453.475.595.59
499.955.745.74
507.586.216.21
497.525.535.53