Basic Information
ID: ALA4832815
Type: Functional
Description: Potency index, ratio of acyclovir EC50 to test compound EC50 for antiviral activity against Human herpesvirus 1 MacIntyre infected in A549 cells assessed as reduction in virus titer treated 1 hr post viral infection followed by replacement with fresh medium with compounds and measured after 48 hrs by MTT assay
Organism: Human alphaherpesvirus 1
Strain: MacIntyre
Cell type: A549
Activity Charts
Bioactivity
Activity Types for Assay ALA4832815
Ratio EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 676.02 | 9.05 | 9.05 |
| 625.94 | 7.58 | 7.58 |
| 621.95 | 8.51 | 8.51 |
| 657.98 | 9.49 | 9.49 |
| 556.83 | 7.80 | 7.80 |
| 710.10 | 9.92 | 9.92 |
| 623.96 | 8.73 | 8.73 |
| 659.95 | 8.33 | 8.33 |