Basic Information
ID: ALA4833232
Type: Binding
Description: Inhibition of NLRP3 inflammasome activation in LPS-stimulated mouse bone marrow-derived macrophages assessed as reduction in IL-1beta secretion preincubated for 30 mins followed by nigericin addition and measured after 30 mins by ELISA
Organism: Mus musculus
Cell type: Macrophage
Activity Charts
Bioactivity
Activity Types for Assay ALA4833232
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 256.30 | 3.58 | 3.58 |
| 364.44 | 0.38 | 0.38 |
| 193.16 | 1.66 | 1.66 |
| 475.50 | 4.21 | 4.21 |
| 394.43 | 4.47 | 4.47 |
| 440.50 | 4.42 | 4.42 |
| 326.35 | 3.70 | 3.70 |
| 408.45 | 4.86 | 4.86 |
| 414.42 | 6.47 | 6.47 |
| 470.53 | 4.35 | 4.35 |
| 327.34 | 3.83 | 3.83 |
| 436.51 | 5.64 | 5.64 |
| 416.86 | 4.69 | 4.69 |
| 553.41 | 5.58 | 5.58 |