Basic Information
ID: ALA4833245
Type: Binding
Description: Inhibition of NLRP3 inflammasome activation in LPS-stimulated mouse bone marrow-derived macrophages assessed as reduction in pro IL-1beta secretion in cell lysate at 2 uM preincubated for 30 mins followed by nigericin addition and measured after 0.5 hrs by Western blot analysis
Organism: Mus musculus
Cell type: Macrophage
Subcellular Fraction: Lysate
Activity Charts
Bioactivity
Activity Types for Assay ALA4833245
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 394.43 | 4.47 | 4.47 |