Assay Report Card

Basic Information

ID: ALA4833247

Type: Binding

Description: Inhibition of NLRP3 inflammasome activation in LPS-stimulated mouse bone marrow-derived macrophages assessed as reduction in ILbeta secretion at 2 uM preincubated for 30 mins followed by nigericin addition and measured after 0.5 hrs by ELISA

Organism: Mus musculus

Cell type: Macrophage

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
394.434.474.47