Assay Report Card

Basic Information

ID: ALA4833258

Type: Binding

Description: Inhibition of AIM2 inflammasome activation in LPS-stimulated mouse bone marrow-derived macrophages assessed as reduction in IL-1beta secretion at 2 uM preincubated for 30 mins followed by poly-(dA:dT) addition and measured after 4 hrs by ELISA

Organism: Mus musculus

Cell type: Macrophage

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
394.434.474.47