Basic Information
ID: ALA4833267
Type: Binding
Description: Inhibition of NLRP3 inflammasome activation in LPS-stimulated mouse bone marrow-derived macrophages assessed as reduction in ASC polymerization at 1 to 4 uM preincubated for 30 mins followed by nigericin addition and measured after 0.5 hrs by DAPI staining based confocal scanning microscopy
Organism: Mus musculus
Cell type: Macrophage
Activity Charts
Bioactivity
Activity Types for Assay ALA4833267
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 394.43 | 4.47 | 4.47 |