Basic Information
ID: ALA4833269
Type: Binding
Description: Inhibition of NLRP3 inflammasome activation in LPS-stimulated mouse bone marrow-derived macrophages assessed as reduction in NEK7-NLRP3 protein-protein interaction preincubated for 30 mins followed by nigericin addition and measured after 30 mins by immunoprecipitation method
Organism: Mus musculus
Cell type: Macrophage
Activity Charts
Bioactivity
Activity Types for Assay ALA4833269
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 394.43 | 4.47 | 4.47 |