Basic Information
ID: ALA4833456
Type: Binding
Description: Inhibition of 8-anilinonaphthalene-l-sulfonic acid binding to TTR V3OM mutant (unknown origin) expressed in Escherichia coli assessed as ANS saturation ratio at 400 uM incubated for 1 hr in presence of 7.5 uM ANS by fluorescence method (Rvb = 56 +/- 2.3%)
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4833456
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 232.24 | 1.42 | 1.42 |
| 290.32 | 1.26 | 1.26 |
| 328.41 | 2.14 | 2.14 |
| 248.72 | 2.52 | 2.52 |
| 250.34 | 3.57 | 3.57 |
| 468.37 | 2.11 | 2.11 |
| 299.80 | 2.00 | 2.00 |
| 239.31 | 1.31 | 1.31 |
| 371.35 | 2.48 | 2.48 |
| 269.13 | 4.00 | 4.00 |
| 356.06 | 5.86 | 5.86 |
| 209.25 | -0.13 | -0.13 |
| 361.83 | 3.55 | 3.55 |
| 290.79 | 3.40 | 3.40 |
| 320.34 | 2.73 | 2.73 |
| 250.20 | 3.04 | 3.04 |
| 283.11 | -0.37 | -0.37 |
| 301.39 | 2.96 | 2.96 |
| 318.76 | 3.81 | 3.81 |
| 325.45 | 3.77 | 3.77 |
| 293.32 | 4.03 | 4.03 |
| 334.17 | 2.89 | 2.89 |
| 298.30 | 2.75 | 2.75 |
| 256.10 | 2.01 | 2.01 |
| 363.80 | 3.29 | 3.29 |
| 279.38 | 2.98 | 2.98 |
| 273.24 | 2.55 | 2.55 |
| 329.23 | 2.73 | 2.73 |
| 307.39 | 2.77 | 2.77 |
| 488.02 | 3.31 | 3.31 |
| 308.33 | 3.61 | 3.61 |
| 376.14 | 4.56 | 4.56 |
| 450.71 | 9.16 | 9.16 |
| 347.40 | 0.44 | 0.44 |
| 450.35 | 5.04 | 5.04 |
| 329.35 | 2.97 | 2.97 |
| 359.67 | 6.04 | 6.04 |
| 365.34 | 7.00 | 7.00 |
| 308.12 | 4.50 | 4.50 |
| 305.37 | 2.37 | 2.37 |
| 424.49 | 5.50 | 5.50 |
| 366.46 | 5.25 | 5.25 |
| 210.19 | 0.62 | 0.62 |