Basic Information
ID: ALA4833628
Type: Binding
Description: Inhibition of gamma secretase (unknown origin) expressed in HEK293 cells assessed as reduction of A-beta40 levels using C100-FLAG as substrate incubated for 2 hrs by sandwich ELISA
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Gamma-secretase(ALA2094135)
Document: ALA4831543
Inhibition of gamma secretase (unknown origin) expressed in HEK293 cells assessed as reduction of A-beta40 levels using C100-FLAG as substrate incubated for 2 hrs by sandwich ELISA: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4833628
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 1055.33 | ||
| 1865.34 | ||
| 1845.43 | ||
| 1101.40 | ||
| 2248.84 | ||
| 2175.87 | ||
| 1849.42 | ||
| 1719.19 | ||
| 2019.64 | ||
| 1921.45 | ||
| 1963.53 | ||
| 1803.35 | ||
| 1747.24 | ||
| 2191.78 | ||
| 1921.45 | ||
| 1963.53 | ||
| 1907.42 | ||
| 1831.41 | ||
| 724.94 | 3.88 | 3.88 |
| 1648.11 | ||
| 2005.61 | ||
| 1775.30 | ||
| 1791.34 |