Assay Report Card

Basic Information

ID: ALA4833707

Type: Functional

Description: Antitumor activity against human Pfeiffer cells harboring EZH2 A677G mutant xenografted in NCG mouse assessed as tumor growth inhibition at 200 mg/kg, po BID via gavage measured after 28 days relative to control

Organism: Homo sapiens

Cell type: Pfeiffer

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
572.754.734.73
610.804.904.90